Job Description

Position Description:

Associate Principal Scientist-Data Rich Measurements

The Data-Rich Measurements (DRM) Group within Analytical R&D Enabling Capabilities organization is seeking a highly motivated individual as an Associate Principal Scientist at its West Point, Pennsylvania location.

The DRM group is responsible and accountable for executing a modality agnostic integrated analytics strategy across our Research & Development Division. This includes the proactive assessment of enabling opportunities as programs enter the development pipeline and progress along stage gates towards the late stage and prior to the supply space.

In this role, you will work with a highly collaborative and motivated team of scientists in our company's Analytical Research and Development in partnership with process development scientists and engineers primarily for the vaccines' portfolio with potential extension to other modalities. This is a laboratory-based role where you will partner with a diverse team of scientists to integrate process analytical technologies (PAT) to pipeline programs to deliver on the development of robust, cost-effective processes while incorporating learnings to influence integrated process control strategies.

The individual will serve as a PAT subject matter expert on program teams and apply a diverse PAT toolkit such as (e.g., online UPLC, Raman, FTIR coupled with advanced chemometric methodologies) in support of early to late-stage programs. The selected individual will proactively advocate for the use of PAT to enable business outcomes by partnering across our Company's network with process, quality, and manufacturing teams to identify enabling opportunities.

This role will also be accountable for developing, optimizing, and executing on phase appropriate validation strategies for online/in-line/at-line methods to monitor and control drug substance and drug product quality attributes in the development space with the intent of enabling seamless transfers to the commercialization space. Additionally, the selected individual will be expected to maintain a strong internal and external network to proactively identify technologies while championing their evaluation and their successful incorporation to existing workflows.

Applicants must have effective communications skills (both oral and written), show scientific curiosity demonstrated through research and publications. As a member of our team, you will be joining scientific problem solvers who are dedicated to creating the life-changing medicines and vaccines of tomorrow.

Position Qualifications:

Education Minimum Requirements:

• Ph.D. in Chemistry or related field with a minimum of 4+ years of relevant experience OR a Masters degree with a minimum of 8+ years of experience

Required Experience and Skills:

• Knowledge of vaccine process development and pilot scale manufacturing

• Proficiency in the use of data-driven qualitative and quantitative chemometric model building approaches (MVDA)

• Experience in areas such as, continuous monitoring using process analytical tools, or lab automation/informatics.

• Ability to deliver complex objectives under aggressive timelines in a rapidly changing environment.

• Demonstrated scientific ability through publications and presentations in scientific conferences.

• Excellent verbal and written communication skills, demonstrated creativity, and strong interpersonal skills.

• Ability to learn new concepts in measurement sciences outside of core expertise and training and the application to problem solving is required

• Ability to work in a team environment with cross-functional interactions is essential

• Evidence of strong cross-functional collaboration in an industrial setting

Preferred Experience and Skills:

• Familiarity with late-stage CMC analytical deliverables including development and the successful execution of GMP validation protocols and tech transfers to commercial laboratories.

• Proficiency in the use of data-driven qualitative and quantitative chemometric model building approaches (MVDA)

• Experience in areas such as, continuous monitoring using process analytical tools, or lab automation/informatics.

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NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

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Employee Status:

Relocation:

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Flexible Work Arrangements:

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Job Posting End Date:

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date:10/04/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R308981