Job Description

Our Company Future Talent Program features internships that last 10-12 weeks and may include one or more projects. For you: these positions in our Company's Research Labs will provide you with a great development opportunity and a chance to see if we are the right company for your long-term goals.For us: we get to meet the best and brightest individuals who represent the future of scientific endeavor in the US.

We are seeking candidates with a passion for scientific research, excellent academic performance, communication skills, teamwork, and the ability to work in a multi-functional environment. A strong science background in applied biology, biochemistry, chemistry or related laboratory settings is essential. Applicants with previous research experience in the listed areas are highly preferred. You will be provided with laptops and access to state-of-the-art lab equipment as necessary to perform the role. This is a paid internship targeted to start in June 2025 and run for 10-12 weeks.Potential involvement in a scientific publication may occur as a result of the research undertaken during the internship.

The department of Protein & Structural Chemistry is offering internships in the following disciplines:

Structural Chemistry (Rahway, NJ; West Point, PA; South San Francisco, CA)

The Structural Chemistry groups use X-ray crystallography and Cryo-electron microscopy to determine structures of drug/target complexes, biologics, and other relevant biological macromolecules to enable structure-based drug discovery. The successful candidate will work to support drug discovery with structural information using some or all of the following methods: preparative protein purification, characterization using SDS-PAGE, spectroscopic and analytical chromatographic methods, biochemical and biophysical pre-crystallization assays, crystallization screening and crystal optimization, crystal harvesting, grid preparation for Cryo-EM, and data collection, processing, and structure determination and critical analysis of protein-ligand structural data. Some molecular biology or protein biochemistry lab experience is required for this position.

Protein Chemistry (West Point, PA only)

The Protein Chemistry group enables crystallography and cryo-EM structural studies by providing high quality, well-characterized recombinant proteins throughout our Company. The PC group also develops methods to design engineered proteins with increased stability and improved solution behavior as well methods for membrane protein stabilization. The successful candidate will be involved in construct design, expression, purification and biophysical characterization of recombinant proteins to support various drug discovery activities. Some molecular biology or protein biochemistry lab experience is required for this position.

Interns will be responsible for accurate electronic notebook recording, safe laboratory practices, and presentation of data and their interpretation to a team of scientists. The intern will also attend departmental and team meetings to gain a wider perspective of the drug development process in the pharmaceutical industry.

**Please note when applying for this position,the candidate must have consent from PI. If the candidateis selected for an interview, the applicant must be prepared to submit letters of recommendation and a brief research statement and a copy of transcripts. Applicant must select location when applying for this position in those cases where multiple locations are listed **

Required Education, Experience and Skills:

• Candidates must be pursuing BS/BA or Master's/Ph.D. degree in related field with demonstrated interest/experience in research areas relevant to the drug discovery process

• Candidates must have basic laboratory skills and research experience such as: structural biology, protein biochemistry, biophysics, BioNMR, mass spectrometry, molecular biology, protein expression and purification, protein characterization using biochemical and biophysical techniques, and safe lab practices.

• Candidates must have completed at least two years of studies toward BS/BA degree or at least 1 year towards Master's/PhD at time of internship (Summer 2025)

• Candidates must be enrolled in an academic program at the time of the application and be continuing education for at least 1 semester once internship completes (Fall 2025)

• Candidates must be available for full-time, on-site employment for 10-12 weeks during the months ofJune - August 2025

Preferred Experience and Skills:

• Candidates should have significant interest in protein structure/function

• Candidates should have experience with preparation of challenging biological macromolecules such as membrane proteins, or characterizing proteins using functional assays or techniques that measure ligand binding

• Candidates should have GPA of 3.0 or higher

Under New York City, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate's relevant skills, experience, and education.

Expected salary range:

$39,600.00-$105,500.00

FTP2025

MRL2025

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Requisition ID:R310894